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Atezolizumab Plus Bevacizumab as First-line Treatment for Patients With Metastatic Nonsquamous Non–Small Cell Lung Cancer With High Tumor Mutation Burden: A Nonrandomized Controlled Trial
IMPORTANCE: Antiangiogenic drug combinations with anti–programmed cell death 1 protein and anti–programmed cell death 1 ligand 1 (PD-L1) agents are a novel treatment option for lung cancer. However, survival remains limited, and the activity of these combinations for tumors with high tumor mutation...
Autores principales: | Provencio, Mariano, Ortega, Ana Laura, Coves-Sarto, Juan, Calvo, Virginia, Marsé-Fabregat, Raquel, Dómine, Manuel, Guirado, María, Carcereny, Enric, Fernández, Natalia, Álvarez, Ruth, Blanco, Remei, León-Mateos, Luis, Sánchez-Torres, José Miguel, Sullivan, Ivana Gabriela, Cobo, Manuel, Sánchez-Hernández, Alfredo, Massuti, Bartomeu, Sierra-Rodero, Belen, Mártinez-Toledo, Cristina, Serna-Blasco, Roberto, Romero, Atocha, Cruz-Bermúdez, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856905/ https://www.ncbi.nlm.nih.gov/pubmed/36520426 http://dx.doi.org/10.1001/jamaoncol.2022.5959 |
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