Cargando…

Capsazepine (CPZ) Inhibits TRPC6 Conductance and Is Protective in Adriamycin-Induced Nephropathy and Diabetic Glomerulopathy

Reactive oxygen species (ROS), which excessively arise in diabetes and systemic inflammatory diseases, modify cellular lipids and cellular lipid composition leading to altered biophysical properties of cellular membranes. The impact of lipid peroxidation on transmembrane signaling routes is not yet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hagmann, Henning, Khayyat, Naghmeh Hassanzadeh, Matin, Mahsa, Oezel, Cem, Chen, He, Schauss, Astrid, Schell, Christoph, Benzing, Thomas, Dryer, Stuart, Brinkkoetter, Paul T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856956/ https://www.ncbi.nlm.nih.gov/pubmed/36672207 http://dx.doi.org/10.3390/cells12020271

Ejemplares similares

Paraoxonase 2 (PON2) Deficiency Reproduces Lipid Alterations of Diabetic and Inflammatory Glomerular Disease and Affects TRPC6 Signaling
por: Hagmann, Henning, et al.
Publicado: (2022)

TRPC6 inactivation does not protect against diabetic kidney disease in streptozotocin (STZ)‐treated Sprague‐Dawley rats
por: Hassanzadeh Khayyat, Naghmeh, et al.
Publicado: (2019)

Polymodal roles of TRPC3 channel in the kidney
por: Khayyat, Naghmeh Hassanzadeh, et al.
Publicado: (2020)

Membrane Interactivity of Capsaicin Antagonized by Capsazepine
por: Mizogami, Maki, et al.
Publicado: (2022)

Development and Evaluation of an FDM Printed Nasal Device for CPZ Solid Nanoparticles
por: To Quoc, Thinh, et al.
Publicado: (2023)

Wuzi Yanzong Pill relieves CPZ-induced demyelination by improving the microenvironment in the brain
por: Li, Yan-Rong, et al.
Publicado: (2022)

Opposite effect of capsaicin and capsazepine on behavioral thermoregulation in insects
por: Olszewska, Justyna, et al.
Publicado: (2011)

Collapsing Glomerulopathy Superimposed on Diabetic Nephropathy
por: Etta, Praveen Kumar, et al.
Publicado: (2019)

ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin
por: Zhang, Lei, et al.
Publicado: (2018)

Carboxypeptidase Z (CPZ) Links Thyroid Hormone and Wnt Signaling Pathways in Growth Plate Chondrocytes
por: Wang, Lai, et al.
Publicado: (2009)

The Effects of TRPC6 Knockout in Animal Models of Kidney Disease
por: Dryer, Stuart E., et al.
Publicado: (2022)

Intrarectal Capsazepine Administration Modulates Colonic Mucosal Health in Mice
por: Kumar, Vibhu, et al.
Publicado: (2022)

IgA nephropathy with podocytic infolding glomerulopathy
por: Wang, Zhouyang, et al.
Publicado: (2023)

Effects of TRPC6 Inactivation on Glomerulosclerosis and Renal Fibrosis in Aging Rats
por: Kim, Eun Young, et al.
Publicado: (2021)

Effects of Pravastatin in Adriamycin-Induced Nephropathy in Rats
por: Mansouri, Esrafil, et al.
Publicado: (2018)

Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels
por: Dryer, Stuart E., et al.
Publicado: (2018)

QSAR and Docking Studies on Capsazepine Derivatives for Immunomodulatory and Anti-Inflammatory Activity
por: Shukla, Aparna, et al.
Publicado: (2014)

Capsazepine decreases corneal pain syndrome in severe dry eye disease
por: Fakih, Darine, et al.
Publicado: (2021)

TRPC6 Inactivation Reduces Albuminuria Induced by Protein Overload in Sprague Dawley Rats
por: Kim, Eun Young, et al.
Publicado: (2022)

Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced-nephropathy rats
por: Zhang, Wei, et al.
Publicado: (2008)

Trpc6 inactivation confers protection in a model of severe nephrosis in rats
por: Kim, Eun Young, et al.
Publicado: (2018)

Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma
por: McDaniel, Lee D., et al.
Publicado: (2017)

Endothelin Receptor A Blockade Is an Ineffective Treatment for Adriamycin Nephropathy
por: Tan, Roderick J., et al.
Publicado: (2013)

Experimental Models to Study Podocyte Biology: Stock-Taking the Toolbox of Glomerular Research
por: Hagmann, Henning, et al.
Publicado: (2018)

A Rare Case of Diabetic Nephropathy and Type III Collagen Glomerulopathy
por: Toro, Diana, et al.
Publicado: (2023)

Vincristine alleviates adriamycin-induced nephropathy through stabilizing actin cytoskeleton
por: Yin, Lei, et al.
Publicado: (2017)

Ameliorating Effect of Gemigliptin on Renal Injury in Murine Adriamycin-Induced Nephropathy
por: Kim, Da Rae, et al.
Publicado: (2017)

Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β‐catenin activity
por: Huang, Xinzhong, et al.
Publicado: (2019)

Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy
por: Kim, Hyung Sook, et al.
Publicado: (2019)

Interaction between Cannabinoid Compounds and Capsazepine in Protection against Acute Pentylenetetrazole-induced Seizure in Mice
por: Naderi, Nima, et al.
Publicado: (2015)

Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer
por: Lee, Jong Hyun, et al.
Publicado: (2016)

Identification of capsazepine as a novel inhibitor of system x(c)(−) and cancer-induced bone pain
por: Fazzari, Jennifer, et al.
Publicado: (2017)

20-Hydroxyeicosatetraenoic Acid (20-HETE) Modulates Canonical Transient Receptor Potential-6 (TRPC6) Channels in Podocytes
por: Roshanravan, Hila, et al.
Publicado: (2016)

The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing
por: Sexton, Jane E., et al.
Publicado: (2016)

TRPC6 Single Nucleotide Polymorphisms and Progression of Idiopathic Membranous Nephropathy
por: Hofstra, Julia M., et al.
Publicado: (2014)

Long-Term Treatment with Gadopentetic Acid or Gadodiamide Increases TRPC5 Expression and Decreases Adriamycin Nuclear Accumulation in Breast Cancer Cells
por: Zhang, Weiheng, et al.
Publicado: (2023)

Glomerulopathy
por: Boaz, Noel T, et al.
Publicado: (2021)

Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis
por: Takiue, Keiichi, et al.
Publicado: (2012)

Glomerular Endothelial Cell Injury and Damage Precedes That of Podocytes in Adriamycin-Induced Nephropathy
por: Sun, Yu Bo Yang, et al.
Publicado: (2013)

Cobrotoxin from Naja naja atra Venom Ameliorates Adriamycin Nephropathy in Rats
por: Wang, Shu-Zhi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tvhjcjf29nue4sktd6d9l49tcu