MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy

Melanoma inhibitory activity/cartilage-derived retinoicacid-sensitive protein (MIA/CD-RAP) is a protein expressed and secreted by chondrocytes and cartilaginous tissues. MIA/CD-RAP-deficient mice develop milder osteoarthritis than wildtype mice. In this study, we investigated MIA/CD-RAP downstream t...

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Detalles Bibliográficos
Autores principales: Staebler, Sebastian, Lichtblau, Adrian, Gurbiel, Slavyana, Schubert, Thomas, Riechers, Alexander, Rottensteiner-Brandl, Ulrike, Bosserhoff, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856983/
https://www.ncbi.nlm.nih.gov/pubmed/36672165
http://dx.doi.org/10.3390/cells12020229

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