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Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naïve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts

Background: Fibroblast-like synoviocytes (FLSs) are essential mediators in the expansive growth and invasiveness of rheumatoid synovitis, and patients with a fibroblastic-rich pauci-immune pathotype respond poorly to currently approved antirheumatic drugs. Galectin-9 (Gal-9) has been reported to dir...

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Detalles Bibliográficos
Autores principales:	Nielsen, Morten A., Køster, Ditte, Mehta, Akul Y., Stengaard-Pedersen, Kristian, Busson, Pierre, Junker, Peter, Hørslev-Petersen, Kim, Hetland, Merete Lund, Østergaard, Mikkel, Hvid, Malene, Leffler, Hakon, Kragstrup, Tue W., Cummings, Richard D., Deleuran, Bent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857341/ https://www.ncbi.nlm.nih.gov/pubmed/36672263 http://dx.doi.org/10.3390/cells12020327

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