Cargando…

A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism

Mixture cure rate models have been developed to analyze failure time data where a proportion never fails. For such data, standard survival models are usually not appropriate because they do not account for the possibility of non-failure. In this context, mixture cure rate models assume that the stud...

Descripción completa

Detalles Bibliográficos
Autores principales: de la Cruz, Rolando, Fuentes, Claudio, Padilla, Oslando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857450/
https://www.ncbi.nlm.nih.gov/pubmed/36673197
http://dx.doi.org/10.3390/e25010056
_version_ 1784873871898312704
author de la Cruz, Rolando
Fuentes, Claudio
Padilla, Oslando
author_facet de la Cruz, Rolando
Fuentes, Claudio
Padilla, Oslando
author_sort de la Cruz, Rolando
collection PubMed
description Mixture cure rate models have been developed to analyze failure time data where a proportion never fails. For such data, standard survival models are usually not appropriate because they do not account for the possibility of non-failure. In this context, mixture cure rate models assume that the studied population is a mixture of susceptible subjects who may experience the event of interest and non-susceptible subjects that will never experience it. More specifically, mixture cure rate models are a class of survival time models in which the probability of an eventual failure is less than one and both the probability of eventual failure and the timing of failure depend (separately) on certain individual characteristics. In this paper, we propose a Bayesian approach to estimate parametric mixture cure rate models with covariates. The probability of eventual failure is estimated using a binary regression model, and the timing of failure is determined using a Weibull distribution. Inference for these models is attained using Markov Chain Monte Carlo methods under the proposed Bayesian framework. Finally, we illustrate the method using data on the return-to-prison time for a sample of prison releases of men convicted of sexual crimes against women in England and Wales and we use mixture cure rate models to investigate the risk factors for long-term and short-term survival of recidivism.
format Online
Article
Text
id pubmed-9857450
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-98574502023-01-21 A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism de la Cruz, Rolando Fuentes, Claudio Padilla, Oslando Entropy (Basel) Article Mixture cure rate models have been developed to analyze failure time data where a proportion never fails. For such data, standard survival models are usually not appropriate because they do not account for the possibility of non-failure. In this context, mixture cure rate models assume that the studied population is a mixture of susceptible subjects who may experience the event of interest and non-susceptible subjects that will never experience it. More specifically, mixture cure rate models are a class of survival time models in which the probability of an eventual failure is less than one and both the probability of eventual failure and the timing of failure depend (separately) on certain individual characteristics. In this paper, we propose a Bayesian approach to estimate parametric mixture cure rate models with covariates. The probability of eventual failure is estimated using a binary regression model, and the timing of failure is determined using a Weibull distribution. Inference for these models is attained using Markov Chain Monte Carlo methods under the proposed Bayesian framework. Finally, we illustrate the method using data on the return-to-prison time for a sample of prison releases of men convicted of sexual crimes against women in England and Wales and we use mixture cure rate models to investigate the risk factors for long-term and short-term survival of recidivism. MDPI 2022-12-28 /pmc/articles/PMC9857450/ /pubmed/36673197 http://dx.doi.org/10.3390/e25010056 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de la Cruz, Rolando
Fuentes, Claudio
Padilla, Oslando
A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title_full A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title_fullStr A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title_full_unstemmed A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title_short A Bayesian Mixture Cure Rate Model for Estimating Short-Term and Long-Term Recidivism
title_sort bayesian mixture cure rate model for estimating short-term and long-term recidivism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857450/
https://www.ncbi.nlm.nih.gov/pubmed/36673197
http://dx.doi.org/10.3390/e25010056
work_keys_str_mv AT delacruzrolando abayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism
AT fuentesclaudio abayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism
AT padillaoslando abayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism
AT delacruzrolando bayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism
AT fuentesclaudio bayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism
AT padillaoslando bayesianmixturecureratemodelforestimatingshorttermandlongtermrecidivism