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Effect of High-Dose Selenium on Postoperative Organ Dysfunction and Mortality in Cardiac Surgery Patients: The SUSTAIN CSX Randomized Clinical Trial

IMPORTANCE: Selenium contributes to antioxidative, anti-inflammatory, and immunomodulatory pathways, which may improve outcomes in patients at high risk of organ dysfunctions after cardiac surgery. OBJECTIVE: To assess the ability of high-dose intravenous sodium selenite treatment to reduce postoper...

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Detalles Bibliográficos
Autores principales:	Stoppe, Christian, McDonald, Bernard, Meybohm, Patrick, Christopher, Kenneth B., Fremes, Stephen, Whitlock, Richard, Mohammadi, Siamak, Kalavrouziotis, Dimitri, Elke, Gunnar, Rossaint, Rolf, Helmer, Philipp, Zacharowski, Kai, Günther, Ulf, Parotto, Matteo, Niemann, Bernd, Böning, Andreas, Mazer, C. David, Jones, Philip M., Ferner, Marion, Lamarche, Yoan, Lamontagne, Francois, Liakopoulos, Oliver J., Cameron, Matthew, Müller, Matthias, Zarbock, Alexander, Wittmann, Maria, Goetzenich, Andreas, Kilger, Erich, Schomburg, Lutz, Day, Andrew G., Heyland, Daren K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857635/ https://www.ncbi.nlm.nih.gov/pubmed/36630120 http://dx.doi.org/10.1001/jamasurg.2022.6855

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