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Current Scenario of Clinical Cancer Research in Latin America and the Caribbean
In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, including a lack of oncology clinical trials. In this...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858272/ https://www.ncbi.nlm.nih.gov/pubmed/36661699 http://dx.doi.org/10.3390/curroncol30010050 |
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author | Gössling, Gustavo Rebelatto, Taiane F. Villarreal-Garza, Cynthia Ferrigno, Ana S. Bretel, Denisse Sala, Raul Giacomazzi, Juliana William, William N. Werutsky, Gustavo |
author_facet | Gössling, Gustavo Rebelatto, Taiane F. Villarreal-Garza, Cynthia Ferrigno, Ana S. Bretel, Denisse Sala, Raul Giacomazzi, Juliana William, William N. Werutsky, Gustavo |
author_sort | Gössling, Gustavo |
collection | PubMed |
description | In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, including a lack of oncology clinical trials. In this article, we will introduce the current status of the region’s clinical research in cancer, with a special focus on academic cancer research groups and investigator-initiated research (IIR) initiatives. Investigators in LAC have strived to improve cancer research despite drawbacks and difficulties in funding, regulatory timelines, and a skilled workforce. Progress has been observed in the representation of this region in clinical trial development and conduct, as well as in scientific productivity. However, most oncology trials in the region have been sponsored by pharmaceutical companies, highlighting the need for increased funding from governments and private foundations. Improvements in obtaining and/or strengthening the LAC cancer research group’s financing will provide opportunities to address cancer therapies and management shortcomings specific to the region. Furthermore, by including this large, ethnic, and genetically diverse population in the world’s research agenda, one may bridge the gap in knowledge regarding the applicability of results of clinical trials now mainly conducted in populations from the Northern Hemisphere. |
format | Online Article Text |
id | pubmed-9858272 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98582722023-01-21 Current Scenario of Clinical Cancer Research in Latin America and the Caribbean Gössling, Gustavo Rebelatto, Taiane F. Villarreal-Garza, Cynthia Ferrigno, Ana S. Bretel, Denisse Sala, Raul Giacomazzi, Juliana William, William N. Werutsky, Gustavo Curr Oncol Review In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, including a lack of oncology clinical trials. In this article, we will introduce the current status of the region’s clinical research in cancer, with a special focus on academic cancer research groups and investigator-initiated research (IIR) initiatives. Investigators in LAC have strived to improve cancer research despite drawbacks and difficulties in funding, regulatory timelines, and a skilled workforce. Progress has been observed in the representation of this region in clinical trial development and conduct, as well as in scientific productivity. However, most oncology trials in the region have been sponsored by pharmaceutical companies, highlighting the need for increased funding from governments and private foundations. Improvements in obtaining and/or strengthening the LAC cancer research group’s financing will provide opportunities to address cancer therapies and management shortcomings specific to the region. Furthermore, by including this large, ethnic, and genetically diverse population in the world’s research agenda, one may bridge the gap in knowledge regarding the applicability of results of clinical trials now mainly conducted in populations from the Northern Hemisphere. MDPI 2023-01-04 /pmc/articles/PMC9858272/ /pubmed/36661699 http://dx.doi.org/10.3390/curroncol30010050 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gössling, Gustavo Rebelatto, Taiane F. Villarreal-Garza, Cynthia Ferrigno, Ana S. Bretel, Denisse Sala, Raul Giacomazzi, Juliana William, William N. Werutsky, Gustavo Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title | Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title_full | Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title_fullStr | Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title_full_unstemmed | Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title_short | Current Scenario of Clinical Cancer Research in Latin America and the Caribbean |
title_sort | current scenario of clinical cancer research in latin america and the caribbean |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858272/ https://www.ncbi.nlm.nih.gov/pubmed/36661699 http://dx.doi.org/10.3390/curroncol30010050 |
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