Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions

Crystal-storing histiocytosis is a rare condition that is histologically characterized by intracellular cytoplasmic crystalline inclusions. It usually presents monoclonal immunoglobulins that deposit within histiocytes, which accumulate and affect different organs of the human body and are commonly...

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Autores principales: Mobarki, Mousa, Papoudou-Bai, Alexandra, Dumollard, Jean Marc, Alhazmi, Abdulaziz H., Musawi, Shaqraa, Madkhali, Mohammed Ali, Muqri, Khalid Y., Péoc’h, Michel, Karpathiou, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858286/
https://www.ncbi.nlm.nih.gov/pubmed/36673081
http://dx.doi.org/10.3390/diagnostics13020271
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author Mobarki, Mousa
Papoudou-Bai, Alexandra
Dumollard, Jean Marc
Alhazmi, Abdulaziz H.
Musawi, Shaqraa
Madkhali, Mohammed Ali
Muqri, Khalid Y.
Péoc’h, Michel
Karpathiou, Georgia
author_facet Mobarki, Mousa
Papoudou-Bai, Alexandra
Dumollard, Jean Marc
Alhazmi, Abdulaziz H.
Musawi, Shaqraa
Madkhali, Mohammed Ali
Muqri, Khalid Y.
Péoc’h, Michel
Karpathiou, Georgia
author_sort Mobarki, Mousa
collection PubMed
description Crystal-storing histiocytosis is a rare condition that is histologically characterized by intracellular cytoplasmic crystalline inclusions. It usually presents monoclonal immunoglobulins that deposit within histiocytes, which accumulate and affect different organs of the human body and are commonly associated with lymphoproliferative conditions, especially those with plasmacytic differentiation. The prognosis of this condition is variable and related to the underlying clinical disease. In this review article, we aim to describe and discuss the clinical and pathological characteristics of crystal-storing histiocytosis based on the available literature and to provide a thorough differential diagnosis.
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spelling pubmed-98582862023-01-21 Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions Mobarki, Mousa Papoudou-Bai, Alexandra Dumollard, Jean Marc Alhazmi, Abdulaziz H. Musawi, Shaqraa Madkhali, Mohammed Ali Muqri, Khalid Y. Péoc’h, Michel Karpathiou, Georgia Diagnostics (Basel) Review Crystal-storing histiocytosis is a rare condition that is histologically characterized by intracellular cytoplasmic crystalline inclusions. It usually presents monoclonal immunoglobulins that deposit within histiocytes, which accumulate and affect different organs of the human body and are commonly associated with lymphoproliferative conditions, especially those with plasmacytic differentiation. The prognosis of this condition is variable and related to the underlying clinical disease. In this review article, we aim to describe and discuss the clinical and pathological characteristics of crystal-storing histiocytosis based on the available literature and to provide a thorough differential diagnosis. MDPI 2023-01-11 /pmc/articles/PMC9858286/ /pubmed/36673081 http://dx.doi.org/10.3390/diagnostics13020271 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mobarki, Mousa
Papoudou-Bai, Alexandra
Dumollard, Jean Marc
Alhazmi, Abdulaziz H.
Musawi, Shaqraa
Madkhali, Mohammed Ali
Muqri, Khalid Y.
Péoc’h, Michel
Karpathiou, Georgia
Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title_full Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title_fullStr Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title_full_unstemmed Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title_short Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
title_sort crystal-storing histiocytosis: the iceberg of more serious conditions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858286/
https://www.ncbi.nlm.nih.gov/pubmed/36673081
http://dx.doi.org/10.3390/diagnostics13020271
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