Exploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation

CONTEXT: Due to the poor prognosis of T-cell acute lymphoblastic leukaemia (T-ALL), there is an urgent need to identify safer and more cost-effective drugs. OBJECTIVE: This study evaluated the antitumour activity of Shuanghuanglian (SHL) on T-ALL cells and elucidated the mechanism. MATERIALS AND MET...

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Detalles Bibliográficos
Autores principales: Yang, You, Yang, Yan, Shen, Yunfu, Liu, Jing, Zeng, Yan, Wei, Chengming, Liu, Chunyan, Pan, Yansha, Guo, Qulian, Zhong, Fangfang, Guo, Ling, Liu, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858418/
https://www.ncbi.nlm.nih.gov/pubmed/36656546
http://dx.doi.org/10.1080/13880209.2023.2168703

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