ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning

Regulation of the Arp2/3 complex is required for productive nucleation of branched actin networks. An emerging aspect of regulation is the incorporation of subunit isoforms into the Arp2/3 complex. Specifically, both ArpC5 subunit isoforms, ArpC5 and ArpC5L, have been reported to fine-tune nucleatio...

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Detalles Bibliográficos
Autores principales: Fäßler, Florian, Javoor, Manjunath G., Datler, Julia, Döring, Hermann, Hofer, Florian W., Dimchev, Georgi, Hodirnau, Victor-Valentin, Faix, Jan, Rottner, Klemens, Schur, Florian K.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858492/
https://www.ncbi.nlm.nih.gov/pubmed/36662867
http://dx.doi.org/10.1126/sciadv.add6495

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