Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics

Cyclic adenosine 3′,5′-monophosphate (cAMP) is a key second messenger in cardiomyocytes responsible for transducing autonomic signals into downstream electrophysiological responses. Previous studies have shown intracellular heterogeneity and compartmentalization of cAMP signaling. However, whether c...

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Detalles Bibliográficos
Autores principales: Caldwell, Jessica L., Lee, I-Ju, Ngo, Lena, Wang, Lianguo, Bahriz, Sherif, Xu, Bing, Bers, Donald M., Navedo, Manuel F., Bossuyt, Julie, Xiang, Yang K., Ripplinger, Crystal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858506/
https://www.ncbi.nlm.nih.gov/pubmed/36662864
http://dx.doi.org/10.1126/sciadv.add5799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858506/
https://www.ncbi.nlm.nih.gov/pubmed/36662864
http://dx.doi.org/10.1126/sciadv.add5799

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