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Actin limits egg aneuploidies associated with female reproductive aging

Aging-related centromeric cohesion loss underlies premature separation of sister chromatids and egg aneuploidy in reproductively older females. Here, we show that F-actin maintains chromatid association after cohesion deterioration in aged eggs. F-actin disruption in aged mouse eggs exacerbated unti...

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Detalles Bibliográficos
Autores principales:	Dunkley, Sam, Mogessie, Binyam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858517/ https://www.ncbi.nlm.nih.gov/pubmed/36662854 http://dx.doi.org/10.1126/sciadv.adc9161

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