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Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review

Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the virus that causes 2019 coronavirus disease (COVID-19), has been isolated from various tissues and body fluids, including the placenta, amniotic fluid, and umbilical cord of newborns. In the last few years, much scientific effort has been di...

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Autores principales: Moza, Andreea, Duica, Florentina, Antoniadis, Panagiotis, Bernad, Elena S., Lungeanu, Diana, Craina, Marius, Bernad, Brenda C., Paul, Corina, Muresan, Cezara, Nitu, Razvan, Dumache, Raluca, Iacob, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858608/
https://www.ncbi.nlm.nih.gov/pubmed/36673058
http://dx.doi.org/10.3390/diagnostics13020245
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author Moza, Andreea
Duica, Florentina
Antoniadis, Panagiotis
Bernad, Elena S.
Lungeanu, Diana
Craina, Marius
Bernad, Brenda C.
Paul, Corina
Muresan, Cezara
Nitu, Razvan
Dumache, Raluca
Iacob, Daniela
author_facet Moza, Andreea
Duica, Florentina
Antoniadis, Panagiotis
Bernad, Elena S.
Lungeanu, Diana
Craina, Marius
Bernad, Brenda C.
Paul, Corina
Muresan, Cezara
Nitu, Razvan
Dumache, Raluca
Iacob, Daniela
author_sort Moza, Andreea
collection PubMed
description Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the virus that causes 2019 coronavirus disease (COVID-19), has been isolated from various tissues and body fluids, including the placenta, amniotic fluid, and umbilical cord of newborns. In the last few years, much scientific effort has been directed toward studying SARS-CoV-2, focusing on the different features of the virus, such as its structure and mechanisms of action. Moreover, much focus has been on developing accurate diagnostic tools and various drugs or vaccines to treat COVID-19. However, the available evidence is still scarce and consistent criteria should be used for diagnosing vertical transmission. Applying the PRISMA ScR guidelines, we conducted a scoping review with the primary objective of identifying the types, and examining the range, of available evidence of vertical transmission of SARS-CoV-2 from mother to newborn. We also aimed to clarify the key concepts and criteria for diagnosis of SARS-CoV-2 vertical infection in neonates and summarize the existing evidence and advance the awareness of SARS-CoV-2 vertical infection in pregnancy. Most studies we identified were case reports or case series (about 30% of poor quality and inconsistent reporting of the findings). Summarizing the existing classification criteria, we propose an algorithm for consistent diagnosis. Registration: INPLASY2022120093.
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spelling pubmed-98586082023-01-21 Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review Moza, Andreea Duica, Florentina Antoniadis, Panagiotis Bernad, Elena S. Lungeanu, Diana Craina, Marius Bernad, Brenda C. Paul, Corina Muresan, Cezara Nitu, Razvan Dumache, Raluca Iacob, Daniela Diagnostics (Basel) Review Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the virus that causes 2019 coronavirus disease (COVID-19), has been isolated from various tissues and body fluids, including the placenta, amniotic fluid, and umbilical cord of newborns. In the last few years, much scientific effort has been directed toward studying SARS-CoV-2, focusing on the different features of the virus, such as its structure and mechanisms of action. Moreover, much focus has been on developing accurate diagnostic tools and various drugs or vaccines to treat COVID-19. However, the available evidence is still scarce and consistent criteria should be used for diagnosing vertical transmission. Applying the PRISMA ScR guidelines, we conducted a scoping review with the primary objective of identifying the types, and examining the range, of available evidence of vertical transmission of SARS-CoV-2 from mother to newborn. We also aimed to clarify the key concepts and criteria for diagnosis of SARS-CoV-2 vertical infection in neonates and summarize the existing evidence and advance the awareness of SARS-CoV-2 vertical infection in pregnancy. Most studies we identified were case reports or case series (about 30% of poor quality and inconsistent reporting of the findings). Summarizing the existing classification criteria, we propose an algorithm for consistent diagnosis. Registration: INPLASY2022120093. MDPI 2023-01-09 /pmc/articles/PMC9858608/ /pubmed/36673058 http://dx.doi.org/10.3390/diagnostics13020245 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Moza, Andreea
Duica, Florentina
Antoniadis, Panagiotis
Bernad, Elena S.
Lungeanu, Diana
Craina, Marius
Bernad, Brenda C.
Paul, Corina
Muresan, Cezara
Nitu, Razvan
Dumache, Raluca
Iacob, Daniela
Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title_full Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title_fullStr Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title_full_unstemmed Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title_short Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection—A Scoping Review
title_sort outcome of newborns with confirmed or possible sars-cov-2 vertical infection—a scoping review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858608/
https://www.ncbi.nlm.nih.gov/pubmed/36673058
http://dx.doi.org/10.3390/diagnostics13020245
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