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High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes

The DNA Damage Response (DDR) pathways sense DNA damage and coordinate robust DNA repair and bypass mechanisms. A series of repair proteins are recruited depending on the type of breaks and lesions to ensure overall survival. An increase in glucose levels was shown to induce genome instability, yet...

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Detalles Bibliográficos
Autores principales: Rahmoon, Mai A., Elghaish, Reem A., Ibrahim, Aya A., Alaswad, Zina, Gad, Mohamed Z., El-Khamisy, Sherif F., Elserafy, Menattallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858638/
https://www.ncbi.nlm.nih.gov/pubmed/36672885
http://dx.doi.org/10.3390/genes14010144