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Altered Left Ventricular Rat Gene Expression Induced by the Myosin Activator Omecamtiv Mecarbil

To explore the impact of omecamtiv mecarbil (OM) on the gene expression profile in adult male rats. Fourteen male Wistar rats were randomly assigned to a single OM (1.2 mg/kg/h; n = 6) or placebo (n = 8) 30-min infusion. Echocardiography was performed before and after OM infusion. Seven days after i...

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Detalles Bibliográficos
Autores principales: El Oumeiri, Bachar, Dewachter, Laurence, Van de Borne, Philippe, Hubesch, Géraldine, Melot, Christian, Jespers, Pascale, Stefanidis, Constantin, Mc Entee, Kathleen, Vanden Eynden, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858687/
https://www.ncbi.nlm.nih.gov/pubmed/36672863
http://dx.doi.org/10.3390/genes14010122