Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial

BACKGROUND: Satisfactory treatment is often lacking for spasticity, a highly prevalent motor disorder in patients with spinal cord injury (SCI). Low concentrations of riluzole potently reduce the persistent sodium current, the post-SCI increase in which contributes to spasticity. The repurposing of...

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Detalles Bibliográficos
Autores principales: Cotinat, Maëva, Boquet, Isabelle, Ursino, Moreno, Brocard, Cécile, Jouve, Elisabeth, Alberti, Corinne, Bensoussan, Laurent, Viton, Jean-Michel, Brocard, Frédéric, Blin, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858801/
https://www.ncbi.nlm.nih.gov/pubmed/36662869
http://dx.doi.org/10.1371/journal.pone.0276892

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