Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair

Flap endonuclease 1 (FEN1) is an essential enzyme that removes RNA primers and base lesions during DNA lagging strand maturation and long-patch base excision repair (BER). It plays a crucial role in maintaining genome stability and integrity. FEN1 is also implicated in RNA processing and biogenesis....

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Detalles Bibliográficos
Autores principales: Laverde, Eduardo E., Polyzos, Aris A., Tsegay, Pawlos P., Shaver, Mohammad, Hutcheson, Joshua D., Balakrishnan, Lata, McMurray, Cynthia T., Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859040/
https://www.ncbi.nlm.nih.gov/pubmed/36672839
http://dx.doi.org/10.3390/genes14010098

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