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A Missense Variant in CASKIN1’s Proline-Rich Region Segregates with Psychosis in a Three-Generation Family

The polygenic nature of schizophrenia (SCZ) implicates many variants in disease development. Rare variants of high penetrance have been shown to contribute to the disease prevalence. Whole-exome sequencing of a large three-generation family with SCZ and bipolar disorder identified a single segregati...

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Detalles Bibliográficos
Autores principales:	Wahbeh, Marah H., Peng, Xi, Bacharaki, Sofia, Hatzimanolis, Alexandros, Dimitrakopoulos, Stefanos, Wohler, Elizabeth, Yang, Xue, Yovo, Christian, Maher, Brady J., Sobreira, Nara, Stefanis, Nikos C., Avramopoulos, Dimitrios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859343/ https://www.ncbi.nlm.nih.gov/pubmed/36672919 http://dx.doi.org/10.3390/genes14010177

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