Cytosolic TGM2 promotes malignant progression in gastric cancer by suppressing the TRIM21‐mediated ubiquitination/degradation of STAT1 in a GTP binding‐dependent modality

BACKGROUND: Previous studies have revealed the critical role of transglutaminase 2 (TGM2) as a potential therapeutic target in cancers, but the oncogenic roles and underlying mechanisms of TGM2 in gastric cancer (GC) are not fully understood. In this study, we examined the role and potential mechani...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Li, Qingya, Yang, Jing, Xu, Penghui, Xuan, Zhe, Xu, Jianghao, Xu, Zekuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859732/
https://www.ncbi.nlm.nih.gov/pubmed/36353796
http://dx.doi.org/10.1002/cac2.12386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859732/
https://www.ncbi.nlm.nih.gov/pubmed/36353796
http://dx.doi.org/10.1002/cac2.12386

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