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Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS

DNA methylation is a critical epigenetic mark in mammalian cells. Many aspects of DNA methylation maintenance have been characterized; however, the exact kinetics of post-replicative methylation maintenance remain a subject of debate. Here we develop isolation of DNA by 5-ethynyl-deoxyuridine labell...

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Detalles Bibliográficos
Autores principales: Stewart-Morgan, Kathleen R., Requena, Cristina E., Flury, Valentin, Du, Qian, Heckhausen, Zoe, Hajkova, Petra, Groth, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859752/
https://www.ncbi.nlm.nih.gov/pubmed/36635504
http://dx.doi.org/10.1038/s41556-022-01048-x