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Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture

The prenatal exposure to ethanol (Eth), fluconazole (FLUCO) and sodium valproate (VPA) is related to effects on development, producing characteristic syndromic pictures. Among embryotoxic effects described for the three molecules, the alteration on craniofacial morphogenesis is a common feature in h...

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Detalles Bibliográficos
Autores principales: Metruccio, Francesca, Battistoni, Maria, Di Renzo, Francesca, Moretto, Angelo, Menegola, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859839/
https://www.ncbi.nlm.nih.gov/pubmed/36385218
http://dx.doi.org/10.1007/s00204-022-03410-2