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Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture
The prenatal exposure to ethanol (Eth), fluconazole (FLUCO) and sodium valproate (VPA) is related to effects on development, producing characteristic syndromic pictures. Among embryotoxic effects described for the three molecules, the alteration on craniofacial morphogenesis is a common feature in h...
Autores principales: | Metruccio, Francesca, Battistoni, Maria, Di Renzo, Francesca, Moretto, Angelo, Menegola, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859839/ https://www.ncbi.nlm.nih.gov/pubmed/36385218 http://dx.doi.org/10.1007/s00204-022-03410-2 |
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