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Trophoblast Stem-Cell-Derived Exosomes Alleviate Cardiotoxicity of Doxorubicin via Improving Mfn2-Mediated Mitochondrial Fusion

Doxorubicin (Dox) is an anticancer drug widely used in tumor chemotherapy, but it has the side-effect of cardiotoxicity, which is closely related to mitochondrial damage. Mitochondrial dynamics is a quality control mechanism that usually helps to maintain a healthy mitochondrial pool. Trophoblast st...

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Detalles Bibliográficos
Autores principales: Duan, Junfeng, Liu, Xiaoli, Shen, Song, Tan, Xi, Wang, Yi, Wang, Lian, Kang, Lina, Wang, Kun, Wei, Zhonghai, Qi, Yu, Hu, Lei, Xu, Biao, Gu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859904/
https://www.ncbi.nlm.nih.gov/pubmed/36609664
http://dx.doi.org/10.1007/s12012-022-09774-2

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