Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin

Following binding to the thin filament, β-cardiac myosin couples ATP-hydrolysis to conformational rearrangements in the myosin motor that drive myofilament sliding and cardiac ventricular contraction. However, key features of the cardiac-specific actin-myosin interaction remain uncertain, including...

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Detalles Bibliográficos
Autores principales: Doran, Matthew H., Rynkiewicz, Michael J., Rasicci, David, Bodt, Skylar M.L., Barry, Meaghan E., Bullitt, Esther, Yengo, Christopher M., Moore, Jeffrey R., Lehman, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859928/
https://www.ncbi.nlm.nih.gov/pubmed/36633586
http://dx.doi.org/10.1085/jgp.202213267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859928/
https://www.ncbi.nlm.nih.gov/pubmed/36633586
http://dx.doi.org/10.1085/jgp.202213267

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