Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements

CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. While attempts have been made to develop such systems in Aedes aegypti, none have been able to match the high drive efficiency observed in Anopheles species. Here we generate Ae. aegypti transgenic lin...

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Detalles Bibliográficos
Autores principales: Anderson, Michelle A. E., Gonzalez, Estela, Ang, Joshua X. D., Shackleford, Lewis, Nevard, Katherine, Verkuijl, Sebald A. N., Edgington, Matthew P., Harvey-Samuel, Tim, Alphey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860013/
https://www.ncbi.nlm.nih.gov/pubmed/36670107
http://dx.doi.org/10.1038/s41467-023-36029-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860013/
https://www.ncbi.nlm.nih.gov/pubmed/36670107
http://dx.doi.org/10.1038/s41467-023-36029-7

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