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Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. While attempts have been made to develop such systems in Aedes aegypti, none have been able to match the high drive efficiency observed in Anopheles species. Here we generate Ae. aegypti transgenic lin...
Autores principales: | Anderson, Michelle A. E., Gonzalez, Estela, Ang, Joshua X. D., Shackleford, Lewis, Nevard, Katherine, Verkuijl, Sebald A. N., Edgington, Matthew P., Harvey-Samuel, Tim, Alphey, Luke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860013/ https://www.ncbi.nlm.nih.gov/pubmed/36670107 http://dx.doi.org/10.1038/s41467-023-36029-7 |
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