Epigenetic biomarkers to track differentiation of pluripotent stem cells

Quality control of induced pluripotent stem cells remains a challenge. For validation of the pluripotent state, it is crucial to determine trilineage differentiation potential toward endoderm, mesoderm, and ectoderm. Here, we report GermLayerTracker, a combination of site-specific DNA methylation (D...

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Detalles Bibliográficos
Autores principales: Schmidt, Marco, Zeevaert, Kira, Elsafi Mabrouk, Mohamed H., Goetzke, Roman, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860076/
https://www.ncbi.nlm.nih.gov/pubmed/36460001
http://dx.doi.org/10.1016/j.stemcr.2022.11.001

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