Syringic acid demonstrates better anti-apoptotic, anti-inflammatory and antioxidative effects than ascorbic acid via maintenance of the endogenous antioxidants and downregulation of pro-inflammatory and apoptotic markers in DMN-induced hepatotoxicity in rats

Dimethyl nitrosamine (DMN) is a known hepatotoxin, carcinogen, and mutagen. This study is therefore carried out to investigate the therapeutic effects of syringic acid (SYRA) and ascorbic acid (ASCA) in DMN-induced hepatic injury in rats. Following DMN administrations, malondialdehyde (MDA), nitric...

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Detalles Bibliográficos
Autores principales: Adeyi, Olubisi E., Somade, Oluwatobi T., Ajayi, Babajide O., James, Adewale S., Adeyi, Akindele O., Olayemi, Zainab M., Tella, Nafisat B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860106/
https://www.ncbi.nlm.nih.gov/pubmed/36691435
http://dx.doi.org/10.1016/j.bbrep.2023.101428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860106/
https://www.ncbi.nlm.nih.gov/pubmed/36691435
http://dx.doi.org/10.1016/j.bbrep.2023.101428

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