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Mechanistic insights into the nickel-dependent allosteric response of the Helicobacter pylori NikR transcription factor
In Helicobacter pylori, the nickel-responsive NikR transcription factor plays a key role in regulating intracellular nickel concentrations, which is an essential process for survival of this pathogen in the acidic human stomach. Nickel binding to H. pylori NikR (HpNikR) allosterically activates DNA...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860126/ https://www.ncbi.nlm.nih.gov/pubmed/36502919 http://dx.doi.org/10.1016/j.jbc.2022.102785 |