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Mechanistic insights into the nickel-dependent allosteric response of the Helicobacter pylori NikR transcription factor

In Helicobacter pylori, the nickel-responsive NikR transcription factor plays a key role in regulating intracellular nickel concentrations, which is an essential process for survival of this pathogen in the acidic human stomach. Nickel binding to H. pylori NikR (HpNikR) allosterically activates DNA...

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Detalles Bibliográficos
Autores principales:	Baksh, Karina A., Augustine, Jerry, Sljoka, Adnan, Prosser, R. Scott, Zamble, Deborah B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860126/ https://www.ncbi.nlm.nih.gov/pubmed/36502919 http://dx.doi.org/10.1016/j.jbc.2022.102785

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