Genomic landscape of the emerging XDR Salmonella Typhi for mining druggable targets clpP, hisH, folP and gpmI and screening of novel TCM inhibitors, molecular docking and simulation analyses

Typhoid fever is transmitted by ingestion of polluted water, contaminated food, and stool of typhoid-infected individuals, mostly in developing countries with poor hygienic environments. To find novel therapeutic targets and inhibitors, We employed a subtractive genomics strategy towards Salmonella...

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Detalles Bibliográficos
Autores principales: Afzal, Muneeba, Hassan, Syed Shah, Sohail, Saman, Camps, Ihosvany, Khan, Yasmin, Basharat, Zarrin, Karim, Asad, Aurongzeb, Muhammad, Irfan, Muhammad, Salman, Muhammad, Morel, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860245/
https://www.ncbi.nlm.nih.gov/pubmed/36681806
http://dx.doi.org/10.1186/s12866-023-02756-6

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