Cargando…
Enhanced production of acetyl-CoA-based products via peroxisomal surface display in Saccharomyces cerevisiae
Colocalization of enzymes is a proven approach to increase pathway flux and the synthesis of nonnative products. Here, we develop a method for enzyme colocalization using the yeast peroxisomal membrane as an anchor point. Pathway enzymes were fused to the native Pex15 anchoring motif to enable displ...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860249/ https://www.ncbi.nlm.nih.gov/pubmed/36409888 http://dx.doi.org/10.1073/pnas.2214941119 |