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Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection

Platelets play a role not only in hemostasis and thrombosis, but also in inflammation and innate immunity. We previously reported that an activated form of tyrosyl-tRNA synthetase (YRS(ACT)) has an extratranslational activity that enhances megakaryopoiesis and platelet production in mice. Here, we r...

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Detalles Bibliográficos
Autores principales: Morodomi, Yosuke, Kanaji, Sachiko, Sullivan, Brian M., Zarpellon, Alessandro, Orje, Jennifer N., Won, Eric, Shapiro, Ryan, Yang, Xiang-Lei, Ruf, Wolfram, Schimmel, Paul, Ruggeri, Zaverio M., Kanaji, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860251/
https://www.ncbi.nlm.nih.gov/pubmed/36409883
http://dx.doi.org/10.1073/pnas.2212659119