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Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis
The phosphoinositide-3 kinase (PI-3K)/AKT cell survival pathway is an important pathway activated by EGFR signaling. Here we show, that in addition to previously described critical components of this pathway, i.e., the docking protein Gab1, the PI-3K/AKT pathway in epithelial cells is regulated by t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860279/ https://www.ncbi.nlm.nih.gov/pubmed/36417441 http://dx.doi.org/10.1073/pnas.2208947119 |