Modulation of cGAS-STING signaling by PPARα in a mouse model of ischemia-induced retinopathy

In ischemic retinopathy, overactivated retinal myeloid cells are a crucial driving force of pathological angiogenesis and inflammation. The cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING) signaling are key regulators of inflammation. This study aims to investigate the assoc...

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Detalles Bibliográficos
Autores principales: Ma, Xiang, Wu, Wenjing, Liang, Wentao, Takahashi, Yusuke, Cai, Jiyang, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860285/
https://www.ncbi.nlm.nih.gov/pubmed/36409895
http://dx.doi.org/10.1073/pnas.2208934119

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