Hypoxia-Induced Autophagy Is Involved in Radioresistance via HIF1A-Associated Beclin-1 in Glioblastoma Multiforme

Radioresistance is the major factor of glioblastoma multiforme (GBM) treatment failure and relapse. Hypoxia and autophagy are linked to radioresistance and poor prognosis in solid tumors, but mechanisms remain unknown. Thus, we hypothesize that hypoxia may activate autophagy through two critical fac...

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Detalles Bibliográficos
Autores principales: Wei, Jielin, Zhu, Kuikui, Yang, Zhe, Zhou, Ying, Xia, Zihan, Ren, Jinghua, Zhao, Yanxia, Wu, Gang, Liu, Cuiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860297/
https://www.ncbi.nlm.nih.gov/pubmed/36691538
http://dx.doi.org/10.1016/j.heliyon.2023.e12820

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