Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury

Antiretroviral therapy (ART) can attain prolonged undetectable HIV-1 in plasma and cerebrospinal fluid (CSF), but brain injury remains prevalent in people living with HIV-1 infection (PLHIV). We investigated cell-associated (CA)-HIV-1 RNA transcripts in cells in CSF and blood, using the highly sensi...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Kazuo, Zaunders, John, Gates, Thomas M., Levert, Angelique, Butterly, Shannen, Liu, Zhixin, Ishida, Takaomi, Palmer, Sarah, Rae, Caroline D., Jugé, Lauriane, Cysique, Lucette A., Brew, Bruce J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860316/
https://www.ncbi.nlm.nih.gov/pubmed/36413502
http://dx.doi.org/10.1073/pnas.2210584119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860316/
https://www.ncbi.nlm.nih.gov/pubmed/36413502
http://dx.doi.org/10.1073/pnas.2210584119

Ejemplares similares