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Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury

Antiretroviral therapy (ART) can attain prolonged undetectable HIV-1 in plasma and cerebrospinal fluid (CSF), but brain injury remains prevalent in people living with HIV-1 infection (PLHIV). We investigated cell-associated (CA)-HIV-1 RNA transcripts in cells in CSF and blood, using the highly sensi...

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Detalles Bibliográficos
Autores principales:	Suzuki, Kazuo, Zaunders, John, Gates, Thomas M., Levert, Angelique, Butterly, Shannen, Liu, Zhixin, Ishida, Takaomi, Palmer, Sarah, Rae, Caroline D., Jugé, Lauriane, Cysique, Lucette A., Brew, Bruce J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860316/ https://www.ncbi.nlm.nih.gov/pubmed/36413502 http://dx.doi.org/10.1073/pnas.2210584119

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