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VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection
Intravacuolar pathogens need to gradually expand their surrounding vacuole to accommodate the growing number of bacterial offspring during intracellular replication. Here we found that Legionella pneumophila controls vacuole expansion by fine-tuning the generation of lysophospholipids within the vac...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860323/ https://www.ncbi.nlm.nih.gov/pubmed/36413498 http://dx.doi.org/10.1073/pnas.2209149119 |