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VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection

Intravacuolar pathogens need to gradually expand their surrounding vacuole to accommodate the growing number of bacterial offspring during intracellular replication. Here we found that Legionella pneumophila controls vacuole expansion by fine-tuning the generation of lysophospholipids within the vac...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Anderson, D. Eric, Chang, Yuen-Yan, Jarnik, Michal, Machner, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860323/
https://www.ncbi.nlm.nih.gov/pubmed/36413498
http://dx.doi.org/10.1073/pnas.2209149119

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