Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota

Granulopoiesis in the bone marrow adjusts cellular output as demand for neutrophils changes. Reactive granulopoiesis is induced by profound neutropenia, but its mechanism remains to be clarified. We herein explored its mechanisms using mouse models of syngeneic hematopoietic stem cell transplantatio...

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Detalles Bibliográficos
Autores principales: Chen, Xuanzhong, Hashimoto, Daigo, Ebata, Ko, Takahashi, Shuichiro, Shimizu, Yu, Shinozaki, Ryuga, Hasegawa, Yuta, Kikuchi, Ryo, Senjo, Hajime, Yoneda, Kazuki, Zhang, Zixuan, Harada, Shinpei, Hayase, Eiko, Ara, Takahide, Ohigashi, Hiroyuki, Iwakura, Yoichiro, Nakamura, Kiminori, Ayabe, Tokiyoshi, Teshima, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860329/
https://www.ncbi.nlm.nih.gov/pubmed/36409919
http://dx.doi.org/10.1073/pnas.2211230119

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