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Myosin light-chain 4 gene-transfer attenuates atrial fibrosis while correcting autophagic flux dysregulation

OBJECTIVES: To determine the role of MYL4 regulation of lysosomal function and its disturbance in fibrotic atrial cardiomyopathy. BACKGROUND: We have previously demonstrated that the atrial-specific essential light chain protein MYL4 is required for atrial contractile, electrical, and structural int...

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Detalles Bibliográficos
Autores principales:	Zhong, Yuan, Tang, Kai, Nattel, Stanley, Zhai, Ming, Gong, Shiyu, Yu, Qing, Zeng, Yanxi, E, Guangxi, Maimaitiaili, Nuerbiyemu, Wang, Jun, Xu, Yawei, Peng, Wenhui, Li, Hailing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860351/ https://www.ncbi.nlm.nih.gov/pubmed/36645977 http://dx.doi.org/10.1016/j.redox.2023.102606

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