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Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications
Biomaterials have ushered the field of tissue engineering and regeneration into a new era with the development of advanced composites. Among these, the composites of inorganic materials with organic polymers present unique structural and biochemical properties equivalent to naturally occurring hybri...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860401/ https://www.ncbi.nlm.nih.gov/pubmed/36714332 http://dx.doi.org/10.1016/j.bioactmat.2023.01.003 |
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author | Sharma, Astha Kokil, Ganesh R. He, Yan Lowe, Baboucarr Salam, Arwa Altalhi, Tariq A. Ye, Qingsong Kumeria, Tushar |
author_facet | Sharma, Astha Kokil, Ganesh R. He, Yan Lowe, Baboucarr Salam, Arwa Altalhi, Tariq A. Ye, Qingsong Kumeria, Tushar |
author_sort | Sharma, Astha |
collection | PubMed |
description | Biomaterials have ushered the field of tissue engineering and regeneration into a new era with the development of advanced composites. Among these, the composites of inorganic materials with organic polymers present unique structural and biochemical properties equivalent to naturally occurring hybrid systems such as bones, and thus are highly desired. The last decade has witnessed a steady increase in research on such systems with the focus being on mimicking the peculiar properties of inorganic/organic combination composites in nature. In this review, we discuss the recent progress on the use of inorganic particle/polymer composites for tissue engineering and regenerative medicine. We have elaborated the advantages of inorganic particle/polymer composites over their organic particle-based composite counterparts. As the inorganic particles play a crucial role in defining the features and regenerative capacity of such composites, the review puts a special emphasis on the various types of inorganic particles used in inorganic particle/polymer composites. The inorganic particles that are covered in this review are categorised into two broad types (1) solid (e.g., calcium phosphate, hydroxyapatite, etc.) and (2) porous particles (e.g., mesoporous silica, porous silicon etc.), which are elaborated in detail with recent examples. The review also covers other new types of inorganic material (e.g., 2D inorganic materials, clays, etc.) based polymer composites for tissue engineering applications. Lastly, we provide our expert analysis and opinion of the field focusing on the limitations of the currently used inorganic/organic combination composites and the immense potential of new generation of composites that are in development. |
format | Online Article Text |
id | pubmed-9860401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-98604012023-01-27 Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications Sharma, Astha Kokil, Ganesh R. He, Yan Lowe, Baboucarr Salam, Arwa Altalhi, Tariq A. Ye, Qingsong Kumeria, Tushar Bioact Mater Article Biomaterials have ushered the field of tissue engineering and regeneration into a new era with the development of advanced composites. Among these, the composites of inorganic materials with organic polymers present unique structural and biochemical properties equivalent to naturally occurring hybrid systems such as bones, and thus are highly desired. The last decade has witnessed a steady increase in research on such systems with the focus being on mimicking the peculiar properties of inorganic/organic combination composites in nature. In this review, we discuss the recent progress on the use of inorganic particle/polymer composites for tissue engineering and regenerative medicine. We have elaborated the advantages of inorganic particle/polymer composites over their organic particle-based composite counterparts. As the inorganic particles play a crucial role in defining the features and regenerative capacity of such composites, the review puts a special emphasis on the various types of inorganic particles used in inorganic particle/polymer composites. The inorganic particles that are covered in this review are categorised into two broad types (1) solid (e.g., calcium phosphate, hydroxyapatite, etc.) and (2) porous particles (e.g., mesoporous silica, porous silicon etc.), which are elaborated in detail with recent examples. The review also covers other new types of inorganic material (e.g., 2D inorganic materials, clays, etc.) based polymer composites for tissue engineering applications. Lastly, we provide our expert analysis and opinion of the field focusing on the limitations of the currently used inorganic/organic combination composites and the immense potential of new generation of composites that are in development. KeAi Publishing 2023-01-11 /pmc/articles/PMC9860401/ /pubmed/36714332 http://dx.doi.org/10.1016/j.bioactmat.2023.01.003 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sharma, Astha Kokil, Ganesh R. He, Yan Lowe, Baboucarr Salam, Arwa Altalhi, Tariq A. Ye, Qingsong Kumeria, Tushar Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title | Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title_full | Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title_fullStr | Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title_full_unstemmed | Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title_short | Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications |
title_sort | inorganic/organic combination: inorganic particles/polymer composites for tissue engineering applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860401/ https://www.ncbi.nlm.nih.gov/pubmed/36714332 http://dx.doi.org/10.1016/j.bioactmat.2023.01.003 |
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