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Nucleotide addition and cleavage by RNA polymerase II: Coordination of two catalytic reactions using a single active site
RNA polymerase II (Pol II) incorporates complementary ribonucleotides into the growing RNA chain one at a time via the nucleotide addition cycle. The nucleotide addition cycle, however, is prone to misincorporation of noncomplementary nucleotides. Thus, to ensure transcriptional fidelity, Pol II bac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860460/ https://www.ncbi.nlm.nih.gov/pubmed/36581202 http://dx.doi.org/10.1016/j.jbc.2022.102844 |