Intrinsically disordered regions that drive phase separation form a robustly distinct protein class

Protein phase separation is thought to be a primary driving force for the formation of membrane-less organelles, which control a wide range of biological functions from stress response to ribosome biogenesis. Among phase-separating (PS) proteins, many have intrinsically disordered regions (IDRs) tha...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ayyam Y., Khaodeuanepheng, Nathan P., Amarasekara, Dhanush L., Correia, John J., Lewis, Karen A., Fitzkee, Nicholas C., Hough, Loren E., Whitten, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860499/
https://www.ncbi.nlm.nih.gov/pubmed/36528065
http://dx.doi.org/10.1016/j.jbc.2022.102801

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