Cargando…
Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860659/ https://www.ncbi.nlm.nih.gov/pubmed/36675570 http://dx.doi.org/10.3390/jcm12020641 |
_version_ | 1784874640181559296 |
---|---|
author | Caviglia, Gian Paolo Garrone, Angela Bertolino, Chiara Vanni, Riccardo Bretto, Elisabetta Poshnjari, Anxhela Tribocco, Elisa Frara, Simone Armandi, Angelo Astegiano, Marco Saracco, Giorgio Maria Bertolusso, Luciano Ribaldone, Davide Giuseppe |
author_facet | Caviglia, Gian Paolo Garrone, Angela Bertolino, Chiara Vanni, Riccardo Bretto, Elisabetta Poshnjari, Anxhela Tribocco, Elisa Frara, Simone Armandi, Angelo Astegiano, Marco Saracco, Giorgio Maria Bertolusso, Luciano Ribaldone, Davide Giuseppe |
author_sort | Caviglia, Gian Paolo |
collection | PubMed |
description | The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016–2021 and compared to the 2001–2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001–2006 (6.7 per 100,000 population/year) to the period 2016–2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016–2021 period, the mean age at diagnosis was 42.0 ± 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients’ management and resources’ allocation. |
format | Online Article Text |
id | pubmed-9860659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98606592023-01-22 Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy Caviglia, Gian Paolo Garrone, Angela Bertolino, Chiara Vanni, Riccardo Bretto, Elisabetta Poshnjari, Anxhela Tribocco, Elisa Frara, Simone Armandi, Angelo Astegiano, Marco Saracco, Giorgio Maria Bertolusso, Luciano Ribaldone, Davide Giuseppe J Clin Med Article The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016–2021 and compared to the 2001–2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001–2006 (6.7 per 100,000 population/year) to the period 2016–2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016–2021 period, the mean age at diagnosis was 42.0 ± 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients’ management and resources’ allocation. MDPI 2023-01-13 /pmc/articles/PMC9860659/ /pubmed/36675570 http://dx.doi.org/10.3390/jcm12020641 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Caviglia, Gian Paolo Garrone, Angela Bertolino, Chiara Vanni, Riccardo Bretto, Elisabetta Poshnjari, Anxhela Tribocco, Elisa Frara, Simone Armandi, Angelo Astegiano, Marco Saracco, Giorgio Maria Bertolusso, Luciano Ribaldone, Davide Giuseppe Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title | Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title_full | Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title_fullStr | Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title_full_unstemmed | Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title_short | Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy |
title_sort | epidemiology of inflammatory bowel diseases: a population study in a healthcare district of north-west italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860659/ https://www.ncbi.nlm.nih.gov/pubmed/36675570 http://dx.doi.org/10.3390/jcm12020641 |
work_keys_str_mv | AT cavigliagianpaolo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT garroneangela epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT bertolinochiara epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT vanniriccardo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT brettoelisabetta epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT poshnjarianxhela epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT triboccoelisa epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT frarasimone epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT armandiangelo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT astegianomarco epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT saraccogiorgiomaria epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT bertolussoluciano epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly AT ribaldonedavidegiuseppe epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly |