Cargando…

Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy

The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-...

Descripción completa

Detalles Bibliográficos
Autores principales: Caviglia, Gian Paolo, Garrone, Angela, Bertolino, Chiara, Vanni, Riccardo, Bretto, Elisabetta, Poshnjari, Anxhela, Tribocco, Elisa, Frara, Simone, Armandi, Angelo, Astegiano, Marco, Saracco, Giorgio Maria, Bertolusso, Luciano, Ribaldone, Davide Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860659/
https://www.ncbi.nlm.nih.gov/pubmed/36675570
http://dx.doi.org/10.3390/jcm12020641
_version_ 1784874640181559296
author Caviglia, Gian Paolo
Garrone, Angela
Bertolino, Chiara
Vanni, Riccardo
Bretto, Elisabetta
Poshnjari, Anxhela
Tribocco, Elisa
Frara, Simone
Armandi, Angelo
Astegiano, Marco
Saracco, Giorgio Maria
Bertolusso, Luciano
Ribaldone, Davide Giuseppe
author_facet Caviglia, Gian Paolo
Garrone, Angela
Bertolino, Chiara
Vanni, Riccardo
Bretto, Elisabetta
Poshnjari, Anxhela
Tribocco, Elisa
Frara, Simone
Armandi, Angelo
Astegiano, Marco
Saracco, Giorgio Maria
Bertolusso, Luciano
Ribaldone, Davide Giuseppe
author_sort Caviglia, Gian Paolo
collection PubMed
description The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016–2021 and compared to the 2001–2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001–2006 (6.7 per 100,000 population/year) to the period 2016–2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016–2021 period, the mean age at diagnosis was 42.0 ± 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients’ management and resources’ allocation.
format Online
Article
Text
id pubmed-9860659
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-98606592023-01-22 Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy Caviglia, Gian Paolo Garrone, Angela Bertolino, Chiara Vanni, Riccardo Bretto, Elisabetta Poshnjari, Anxhela Tribocco, Elisa Frara, Simone Armandi, Angelo Astegiano, Marco Saracco, Giorgio Maria Bertolusso, Luciano Ribaldone, Davide Giuseppe J Clin Med Article The burden of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016–2021 and compared to the 2001–2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001–2006 (6.7 per 100,000 population/year) to the period 2016–2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016–2021 period, the mean age at diagnosis was 42.0 ± 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients’ management and resources’ allocation. MDPI 2023-01-13 /pmc/articles/PMC9860659/ /pubmed/36675570 http://dx.doi.org/10.3390/jcm12020641 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Caviglia, Gian Paolo
Garrone, Angela
Bertolino, Chiara
Vanni, Riccardo
Bretto, Elisabetta
Poshnjari, Anxhela
Tribocco, Elisa
Frara, Simone
Armandi, Angelo
Astegiano, Marco
Saracco, Giorgio Maria
Bertolusso, Luciano
Ribaldone, Davide Giuseppe
Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title_full Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title_fullStr Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title_full_unstemmed Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title_short Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
title_sort epidemiology of inflammatory bowel diseases: a population study in a healthcare district of north-west italy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860659/
https://www.ncbi.nlm.nih.gov/pubmed/36675570
http://dx.doi.org/10.3390/jcm12020641
work_keys_str_mv AT cavigliagianpaolo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT garroneangela epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT bertolinochiara epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT vanniriccardo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT brettoelisabetta epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT poshnjarianxhela epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT triboccoelisa epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT frarasimone epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT armandiangelo epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT astegianomarco epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT saraccogiorgiomaria epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT bertolussoluciano epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly
AT ribaldonedavidegiuseppe epidemiologyofinflammatoryboweldiseasesapopulationstudyinahealthcaredistrictofnorthwestitaly