Cargando…

Ginseng Sprouts Attenuate Mortality and Systemic Inflammation by Modulating TLR4/NF-κB Signaling in an LPS-Induced Mouse Model of Sepsis

Sepsis leads to multi-organ failure due to aggressive systemic inflammation, which is one of the main causes of death clinically. This study aimed to evaluate whether ginseng sprout extracts (GSE) can rescue sepsis and explore its underlying mechanisms. C57BL/6J male mice (n = 15/group) were pre-adm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Seung-Ju, Wang, Jing-Hua, Lee, Jin-Seok, Kang, Ji-Yun, Baek, Dong-Cheol, Kim, Geon-Ho, Ahn, Yo-Chan, Son, Chang-Gue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860726/ https://www.ncbi.nlm.nih.gov/pubmed/36675101 http://dx.doi.org/10.3390/ijms24021583

Ejemplares similares

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells
por: Wan, Jian, et al.
Publicado: (2016)

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
por: Badshah, Haroon, et al.
Publicado: (2016)

Lianqinjiedu decoction attenuates LPS-induced inflammation and acute lung injury in rats via TLR4/NF-κB pathway
por: Deng, Guiming, et al.
Publicado: (2017)

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling
por: Muhammad, Tahir, et al.
Publicado: (2019)

Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway
por: Shi, Min, et al.
Publicado: (2017)

Exogenous Putrescine Enhances Salt Tolerance and Ginsenosides Content in Korean Ginseng (Panax ginseng Meyer) Sprouts
por: Islam, Md. Jahirul, et al.
Publicado: (2021)

CETP Lowers TLR4 Expression Which Attenuates the Inflammatory Response Induced by LPS and Polymicrobial Sepsis
por: Venancio, Tatiana Martins, et al.
Publicado: (2016)

Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression
por: Ahn, Huijeong, et al.
Publicado: (2019)

Inosine Pretreatment Attenuates LPS-Induced Lung Injury through Regulating the TLR4/MyD88/NF-κB Signaling Pathway In Vivo
por: Mao, Bingyong, et al.
Publicado: (2022)

Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells
por: de Sousa, João Antônio Costa, et al.
Publicado: (2023)

Korean Red Ginseng Ameliorates Fatigue via Modulation of 5-HT and Corticosterone in a Sleep-Deprived Mouse Model
por: Kang, Ji-Yun, et al.
Publicado: (2021)

Fermented Sprouts of Codonopsis lanceolata Suppress LPS-Induced Inflammatory Responses by Inhibiting NF-κB Signaling Pathway in RAW 264.7 Macrophages and CD1 Mice
por: Choi, Seung-Hyuk, et al.
Publicado: (2023)

Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
por: Huang, Chi-Han, et al.
Publicado: (2021)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
por: Olmos-Ortiz, A, et al.
Publicado: (2019)

Potential application of ginseng in sepsis:: Applications of ginseng in sepsis
por: Yang, Fuxun, et al.
Publicado: (2023)

Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways
por: Hou, Yue, et al.
Publicado: (2017)

Anti-Neuroinflammatory Effect of the Ethanolic Extract of Black Ginseng through TLR4-MyD88-Regulated Inhibition of NF-κB and MAPK Signaling Pathways in LPS-Induced BV2 Microglial Cells
por: Kim, Kwan-Woo, et al.
Publicado: (2023)

Antifatigue Effects of Panax ginseng C.A. Meyer: A Randomised, Double-Blind, Placebo-Controlled Trial
por: Kim, Hyeong-Geug, et al.
Publicado: (2013)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Metformin attenuates LPS-induced neuronal injury and cognitive impairments by blocking NF-κB pathway
por: Zhou, Chenliang, et al.
Publicado: (2021)

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response
por: Hung, Yung-Li, et al.
Publicado: (2017)

Berberine attenuates septic cardiomyopathy by inhibiting TLR4/NF-κB signalling in rats
por: Chen, Huiqi, et al.
Publicado: (2021)

Hierarchical Machine Learning-Based Growth Prediction Model of Panax ginseng Sprouts in a Hydroponic Environment
por: Kim, Tae Hyong, et al.
Publicado: (2023)

Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway
por: Xiang, Nan-lin, et al.
Publicado: (2016)

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis
por: Qu, Yifan, et al.
Publicado: (2021)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Berberine administrated with different routes attenuates inhaled LPS-induced acute respiratory distress syndrome through TLR4/NF-κB and JAK2/STAT3 inhibition
por: Xu, Guanghui, et al.
Publicado: (2021)

J147 ameliorates sepsis-induced depressive-like behaviors in mice by attenuating neuroinflammation through regulating the TLR4/NF-κB signaling pathway
por: Qiu, Fang, et al.
Publicado: (2023)

Parthenolide attenuates LPS-induced activation of NF-κB in a time-dependent manner in rat myocardium()
por: Xie, Hong, et al.
Publicado: (2012)

METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway
por: Wang, Jinghua, et al.
Publicado: (2019)

Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation
por: Sailaja, Badi Sri, et al.
Publicado: (2021)

Dimethyl Fumarate Protects against Lipopolysaccharide- (LPS-) Induced Sepsis through Inhibition of NF-κB Pathway in Mice
por: Fang, He, et al.
Publicado: (2023)

Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice
por: Qi, Shuang, et al.
Publicado: (2020)

Resveratrol inhibits LPS-induced inflammation through suppressing the signaling cascades of TLR4-NF-κB/MAPKs/IRF3
por: Tong, Wenzhi, et al.
Publicado: (2020)

Allicin Alleviated LPS-Induced Mastitis via the TLR4/NF-κB Signaling Pathway in Bovine Mammary Epithelial Cells
por: Che, Hao-Yu, et al.
Publicado: (2023)

Pycnogenol attenuates atherosclerosis by regulating lipid metabolism through the TLR4–NF-κB pathway
por: Luo, Hong, et al.
Publicado: (2015)

MicroRNA-223 attenuates LPS-induced inflammation in an acute lung injury model via the NLRP3 inflammasome and TLR4/NF-κB signaling pathway via RHOB
por: Yan, Yurong, et al.
Publicado: (2019)

Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway
por: Hou, Jing, et al.
Publicado: (2021)

Huoxiang Zhengqi Oral Liquid Attenuates LPS-Induced Acute Lung Injury by Modulating Short-Chain Fatty Acid Levels and TLR4/NF-κB p65 Pathway
por: Tang, Ruying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_546es51laa4ednrl1andf45bb8