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In Silico Quantification of Intersubject Variability on Aerosol Deposition in the Oral Airway
The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition. Using computational fluid dynamics, deposition of 1–30 µm particles was predicted in 11 CT-based models of the oral airways of...
Autores principales: | Borojeni, Azadeh A. T., Gu, Wanjun, Asgharian, Bahman, Price, Owen, Kuprat, Andrew P., Singh, Rajesh K., Colby, Sean, Corley, Richard A., Darquenne, Chantal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860768/ https://www.ncbi.nlm.nih.gov/pubmed/36678786 http://dx.doi.org/10.3390/pharmaceutics15010160 |
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