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Corneal Adverse Events Associated with SARS-CoV-2/COVID-19 Vaccination: A Systematic Review

Vaccines against coronavirus disease 2019 (COVID-19) have played an important global role in reducing morbidity and mortality from COVID-19 infection. While the benefits of vaccination greatly outweigh the risks, adverse events do occur. Non-ocular adverse effects of the vaccines have been well-docu...

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Detalles Bibliográficos
Autores principales: Kuziez, Lana, Eleiwa, Taher K., Chauhan, Muhammad Z., Sallam, Ahmed B., Elhusseiny, Abdelrahman M., Saeed, Hajirah N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860789/
https://www.ncbi.nlm.nih.gov/pubmed/36680010
http://dx.doi.org/10.3390/vaccines11010166
Descripción
Sumario:Vaccines against coronavirus disease 2019 (COVID-19) have played an important global role in reducing morbidity and mortality from COVID-19 infection. While the benefits of vaccination greatly outweigh the risks, adverse events do occur. Non-ocular adverse effects of the vaccines have been well-documented, but descriptions of ophthalmic effects remain limited. This systematic review aims to provide an overview of reported cases of corneal adverse events after receiving vaccination against COVID-19 and to compile existing clinical data to bring attention to these phenomena. Our review discusses corneal graft rejection, including proposed mechanisms, herpetic keratitis, and other reported corneal complications. Ophthalmologists and primary care physicians should be aware of such possible associations.