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SHIP1 Controls Internal Platelet Contraction and α(IIb)β(3) Integrin Dynamics in Early Platelet Activation

The Src homology 2 domain-containing inositol 5-phosphatase 1 (SHIP1) is known to dephosphorylate PtdIns(3,4,5)P(3) into PtdIns(3,4)P(2) and to interact with several signaling proteins though its docking functions. It has been shown to negatively regulate platelet adhesion and spreading on a fibrino...

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Detalles Bibliográficos
Autores principales: Severin, Sonia, Consonni, Alessandra, Chicanne, Gaëtan, Allart, Sophie, Payrastre, Bernard, Gratacap, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860818/
https://www.ncbi.nlm.nih.gov/pubmed/36674478
http://dx.doi.org/10.3390/ijms24020958